1. Cytokines

Recombinant Human Endostatin (P.pastoris-expressed)

目录号: HY-P7009
产品使用指南

Recombinant Human Endostatin (P。pastoris-expressed) 是一种内源性抗血管新生肽,在细胞质中能够通过调节多种受体来抗肿瘤,例如,抑制血管新生,抑制肿瘤细胞的迁移和入侵。

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Size Price Stock Quantity
10 μg ¥600 In-stock
50 μg ¥1200 In-stock
100 μg ¥1900 In-stock
250 μg   Get quote  

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Synonyms
rHuEndostatin; Collagen alpha-1(XV) chain ; 重组人血管内皮抑制素 (P.pastoris 表达)
Species

Human

Source

P. pastoris

Accession

P39060

Gene ID

80781

Molecular Weight

Approximately 16 kDa

AA Sequence

AHSHRDFQPV LHLVALNSPL SGGMRGIRGA DFQCFQQARA VGLAGTFRAF LSSRLQDLYS IVRRADRAAV PIVNLKDELL FPSWEALFSG SEGPLKPGAR IFSFDGKDVL RHPTWPQKSV WHGSDPNGRR LTESYCETWR TEAPSATGQA SSLLGGRLLG QSAASCHHAY IVLCIENSFM TASK

Biological Activity

The ED50 is 10μg/mL as measured by Endothelial cells.

Appearance

Lyophilized powder.

Formulation

Lyophilized after extensive dialysis against 17 mM citric-phosphate buffer, pH 6.2.

Endotoxin Level

<1 EU/μg, determined by LAL method.

Reconsititution

Reconstitute the lyophilized recombinant Human Endostatin (P.pastoris-expressed) (rHuEndostatin) to 100 µg/mL using ddH2O.

Storage & Stability

Lyophilized recombinant Human Endostatin (P.pastoris-expressed) (rHuEndostatin) is stored at -20°C. After reconstitution, it is stable at 4°C for 2 weeks or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Shipping

Room temperature in continental US; may vary elsewhere.

Background

Recombinant Human Endostatin is an endogenous antiangiogenic peptide with multiple antitumor roles through modulation of various receptors in the plasma membrane, such as suppression of angiogenesis and inhibition of tumor-cell migration and invasion[1]. Recombinant Human Endostatin (rhEndostatin) shows a potent bioactivity and is capable of synergizing with CTX and DDP in suppression of tumor cell growth[2].

Documentation
References
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    [2].

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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产品名称:
Recombinant Human Endostatin (P.pastoris-expressed)
目录号:
HY-P7009
需求量:
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