Terfenadine (Synonyms: (±)-Terfenadine; MDL-991)

目录号: HY-B1193 纯度: 98.26%
产品使用指南

Terfenadine是一种有效的hERG开放通道抑制剂, IC50为204 nM。

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Terfenadine Chemical Structure

Terfenadine Chemical Structure

CAS No. : 50679-08-8

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Size Price Stock Quantity
Free Sample (0.1-0.5 mg)   Apply now  
10 mM * 1 mL in DMSO ¥550 In-stock
100 mg ¥500 In-stock
200 mg   Get quote  
500 mg   Get quote  

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Description

Terfenadine is a potent open-channel blocker of hERG with a mean IC50 of 204 nM. IC50 value: 204 nM Target: HERG Terfenadine normally undergoes extensive first-pass metabolism in the liver to produce an active acidic metabolite. Terfenadine is a widely used, over-the-counter drug to treat allergies.

Solvent & Solubility
In Vitro: 

10 mM in DMSO

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.1201 mL 10.6006 mL 21.2013 mL
5 mM 0.4240 mL 2.1201 mL 4.2403 mL
10 mM 0.2120 mL 1.0601 mL 2.1201 mL
*Please refer to the solubility information to select the appropriate solvent.
References
  • [1].

Molecular Weight

471.67

Formula

C₃₂H₄₁NO₂

CAS No.

50679-08-8

SMILES

OC(C1=CC=C(C(C)(C)C)C=C1)CCCN2CCC(C(C3=CC=CC=C3)(O)C4=CC=CC=C4)CC2

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Shipping

Room temperature in continental US; may vary elsewhere

  • [1].

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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产品名称:
Terfenadine
目录号:
HY-B1193
需求量:

Terfenadine

Cat. No.: HY-B1193

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