EBI-1051 

目录号: HY-111368
产品使用指南

EBI-1051是有高选择性,可口服的 MEK 抑制剂, IC50 为3.9 nM 。

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EBI-1051 Chemical Structure

EBI-1051 Chemical Structure

CAS No. : 1801896-05-8

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Description

EBI-1051 is a highly potent and orally efficacious MEK inhibitor with an IC50 of 3.9 nM.

IC50 & Target

IC50: 3.9 nM (MEK)[1]

Solvent & Solubility
In Vitro: 

10 mM in DMSO

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.9833 mL 9.9163 mL 19.8326 mL
5 mM 0.3967 mL 1.9833 mL 3.9665 mL
10 mM 0.1983 mL 0.9916 mL 1.9833 mL
*Please refer to the solubility information to select the appropriate solvent.
References
  • [1].

Molecular Weight

504.22

Formula

C₁₈H₁₅F₂IN₂O₅

CAS No.

1801896-05-8

SMILES

O=C(NOC(CO)CO)C1=C(NC2=CC=C(I)C=C2F)C(F)=C3C(C=CO3)=C1

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Shipping

Room temperature in continental US; may vary elsewhere

  • [1].

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Inquiry Information

产品名称:
EBI-1051
目录号:
HY-111368
需求量:

EBI-1051

Cat。 No。: HY-111368

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